In 2005, our team, in corporation with indigenous scientists, conducted an international survey, recording iodine deficiency status. Five hundred and seventy five (575) children aged 6-17 years old from different regions of Uzbekistan (n=11) were studied. Three hundred and seventy seven of them (161 boys and 216 girls) underwent body weight and height measurements, FFBM and Fat Body Mass (FBM) estimation using a portable apparatus (Tanita BC-418 MA, UK LTD), ultrasound assessment of thyroid volume using a portable apparatus with a 7.5 – MHz linear transducer (Scanner 100 LC Pie Medical, Phillips Medical Systems Company, Maastricht, The Netherlands), and bone age estimation by ultrasound (Sunlight Bone Age, Israel). Urine Iodine excretion (UIE) was measured in a morning sample by the spectrophotometric method (Sandell-Kolthoff reaction). Median UIE was 76 mcg/L and goiter’s prevalence was 19%. Serum levels of T3, T4, TSH, Tg, anti-TPO and anti-Tg auto-antibodies were within normal limits.

These results were announced at international conferences (European Thyroid Conference, Leipzig 2007 and American Conference of Endocrinology, Toronto 2007) and contributed to legislating on exclusive use of iodized salt. Based on these results, Uzbekistan was characterized by mild iodine deficiency and endemic goiter.

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